One Pot Multicomponent Synthesis, Characterization of Pyranopyrazole Compounds with Novel Catalysed Using Pyruvic Acid
Keywords:
Pyranopyrazole compounds, One Pot Multicomponent, Malonic nitrile, Pyruvic acidAbstract
Owing to the importance of pyranopyrazole supports, several methods for their synthesis were developed. The previous intelligences on the synthesis of pyranopyrazole derivatives smarted many disadvantages which included struggle in the workup, longer reaction time, and high cost of catalyst and use of organic solvents. The present article reports the use of easily available pyruvic acid as a catalyst for multicomponent one pot synthesis using ethyl acetoacetate, malonic nitrite, sub. Aromatic aldehyde and hydrazine hydrate to synthesised pyranopyrazole derivatives. These compounds characterized by physical constant, IR spectra, 1H NMR spectra, were also studied. The presentation in the synthesis of pyranopyrazole derivatives was recognized. The present technique of synthesis of pyranopyrazole derivatives followed a simple technique and easy workup practice. The catalyst used in this reaction was easily available and gave good yield with less time.
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