Assessment of Anti-diabetic Activity of Cassia Siamea Lam Leaves Ethanol Extract
Keywords:
Cassia siamea Lam, diabetes mellitus, α-amylase, phytochemicals, α-amylase inhibitorAbstract
The species of the genus Cassia has been reported for various pharmacological activities and their rich contents of phytochemicals use to treat health related disorders. The different parts of Cassia siamea Lam plant has been traditionally used as a medicine to treat diabetes mellitus related disorders. The assessment study aimed to investigate anti-diabetic activity of locally used medicinal plant Cassia siamea Lam leaves ethanol extract by porcine pancreatic α-amylase enzyme inhibition in vitro assay. A potent enzyme inhibitory activity was showed by the leaves of Cassia siamea Lam ethanol extract. The enzyme assay-guided leaves ethanol extract led to the inhibition activity of enzyme and has potent α-amylase inhibitor content of bioactive phytochemicals. This assessment study that describes the potency of Cassia siamea Lam medicinal plant leaves has been used an alternative medicine to treat disorders of diabetes mellitus.
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