Topological Modeling of log D7.4 of Hydroxylated Aromatic Aldehydes

Authors

  • Sunita Patel Hardia Department of Chemistry, Holkar Science College, Indore,( M.P).452001,India.

Keywords:

Toxicity, logD7.4, topological indices, QSAR, regression analysis

Abstract

The quantitative Structure-Aciivity Relationship (QSAR) was performed for a set of 25 hydroxylated aromatic aldehydes for modeling logD7.4 , responsible for exhibiting toxicity ,using topological indices . The purpose of the study is, therefore, to find out topological dependence of logD7.4 vis-à-vis toxicity. Multiple regression analysis (MLR)was used for obtaining statistically significant models. The results show that statistically significant models are obtained in multi-parametric regression model in that Ss,Xu and MSD are found useful in modeling of logD7.4 .

 

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Published

2015-12-30

How to Cite

Hardia, S. P. (2015). Topological Modeling of log D7.4 of Hydroxylated Aromatic Aldehydes. International Journal of Scientific Research in Chemical Sciences, 2(1), 1–4. Retrieved from https://ijsrcs.isroset.org/index.php/j/article/view/4

Issue

Vol. 2 No. 1 (2015): December

Section

Research Article

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