Green and Efficient Synthesis, Characterization, Biological Activity of Novel Schiff Base Ligand and their Transition Metal Complexes Derived From 4-((E)-(benzo[d]thiazol-2-ylimino) methyl)-2, 6-dimethoxyphenol
Keywords:
Green synthesis, 2-Amino Benzothiazole, Thermal Study, Schiff Base Ligand, Antibacterial ActivityAbstract
The present work, microwave assisted green synthesis of novel Schiff base ligand 4-((E)-(benzo[d]thiazol-2-ylimino)methyl)-2,6-dimethoxyphenol and its transition metal complexes of Co(II), Ni(II), Cu(II), Zn(II),and Cd(II) were prepared under microwave irradiation as a green approach method. The novel Schiff base ligand was recognized by melting point and thin layer chromatography. Characterization was by elemental analysis, Infrared spectra 1HNMR spectra and mass spectroscopy. The metal complexes were identified by melting point, thin layer chromatography and their distinctive Colour. Metal complexes were characterized by Infrared spectroscopy, UV-visible spectroscopy and thermogravimetric analysis. The antibacterial activities of the Schiff base ligand and its metal complexes were tested against Escherichia coli, Staphylococcus aurous and Salmonella Typhi.
References
Azza AA and Abu-Hussen, J. Coord Chem., 59, 157, 2006.
Mladenova R., Ignatova M., Manolova M., Petrova T. and Rashkov I., Eur. J. Polym, 38, 989, 2002.
Iqbal, J., Tirmizi, S. A., and Watto, F.H. Biological properties of chloro-salicylidene aniline and its complexes with Co(II) and Ni(II). Turk J. Biol., 30, pp.1-4, 2006.
Bagihalli, G. B., Patil, S. A., and Badami, P. S. Synthesis, physicochemical Investigation and biological studies of Zn(II) complexes with 1,2,4-triazole Schiff bases. J. Iran Chem. Soc., 6, pp.259-270, 2009.
Mahajan, K., Fahmi, N., and Singh, R. V. Synthesis, characterization and antimicrobial studies of Sb(III) complexes of substituted thioimines. Indian J. Chem., 46A, pp.1221-1225, 2007.
Sharma, K., Singh, R., Fahmi, N., and Singh, R.V., 2010.
Microwave assisted synthesis,characterization and biological evaluation of palladium and platinum complexes with azomethines. Spectrochim. Acta A, 75, pp.422-428, 2010.
Mohanan, K., Kumari, B. S., and Rijulal, G., Microwave assisted synthesis, spectroscopic, thermal and antifungal studies of some lanthanide (III) complexes with heterocyclic bishydrazone. J. Rare Earths, 26, pp.16-21, 2008.
Sun, Y., Machala, M.L., and Castellano, F.N., Controlled microwave synthesis of RuII synthons and chromophores relevant to solar energy conversion. Inorg. Chim. Acta, 363, pp.283-287, 2010.
Garg, R., Saini, M.K., Fahmi, N., and Singh, R.V., Spectroscopic and biochemical studies of some manganese(II), oxovanadium(V) and dioxovanadium(VI) complexes S/O and Ndonor agents synthesized under microwave conditions. Trans. Met. Chem., 31: pp.362-371, 2006.
Mahajan, K., Swami, M., and Singh, R.V., Microwave synthesis, spectral studies, antimicrobial approach and coordination behavior of antimony (III) and bismuth (III) compounds with benzothiazoline. Russ. J. Coord. Chem., 35, pp.179-185, 2009.
Sridhar S.K., Saravanan M. and Ramesh A., Eur.J.Med.Chem., 36, pp.6-15, 2001.
Karthikeyan M.S., Prasad D.J., Poojary B., Bhat K.S., Holla B.S. and Kumari N.S.,Bioorg.Med.Chem., 14, pp.74-82, 2006.
Panneerselvam P, Nair R.R, Vijayalakshmi G.Subramanian E.H., and Sridhar S.K.,Eur.J.Med.Chem. 40, 225, 2005.
Campo R. et al. J. Inorg. Biochem. 89, 74, 2002.
Huang G.S., Liang Y.M., Wu X.L., Liu W.M. and Ma Y.X., Appl. Orgnomet. Chem., 17, 706, 2003.
Adams, J. P. J. Chem. Soc., Perkin Trans. 1, 125, 2000.
Macho, V.; Kralik, M.; Hudec, J.; Cingelova, J., J. Mol. Catal. A: Chem. 69, 209, 2004.
Abbaspour, A.; Esmaeilbeig, A. R.; Jarrahpour, A. A.; Khajeh, B.; Kia, R., Talanta, 58, 397, 2002.
Jarrahpour, A. A.; Motamedifar M.; Pakshir, K.; Hadi, N.; Zarei, M., Molecules, 9, 815, 2004.
Higuchi, M.; Yamamoto, K. Org. Lett, 1, 1881, 1999.
Yildirm L. T., Atakol O., Cryst. Res. Technol. 37, 1352, 2002.
Costamagna J., Vargas J., Latorre R., Alvarado A., Mena G., Coord. Chem. Rev., 119, 67, 1992.
Garnovski A. D., Nivorozhkin A. L., Coord. Chem. Rev., 126, 1, 1993.
Fedtchouk, Lozitsky V.P., Muratov E.N., Mescheriakov A.K., SAR & QSAR Environ. Res.16, 219, 2005.
Shi L., Ge M., Tan S.H., Li H.Q., Song Y.C., Zhu H.L. and Tan R.X., Eur.J.Med.Chem.42, 558, 2007.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors contributing to this journal agree to publish their articles under the Creative Commons Attribution 4.0 International License, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit and that in the event of reuse or distribution, the terms of this license are made clear.
